Toxicity of ibuprofen and perfluorooctanoic acid for risk assessment of mixtures in aquatic and terrestrial environments

González-Naranjo, V. and Boltes, K. (2013) Toxicity of ibuprofen and perfluorooctanoic acid for risk assessment of mixtures in aquatic and terrestrial environments. International Journal of Environmental Science and Technology. ISSN 1735-1472

Full text not available from this repository.
Official URL: http://dx.doi.org/10.1007/s13762-013-0379-9

Abstract

The toxicity of ibuprofen and perfluorooctanoic acid (PFOA) was evaluated individually and in binary combination on two photosynthetic organisms, the green alga Pseudokirchneriella subcapitata, representative of aquatic environments, and the monocotyledonous Sorghum bicolor, for terrestrial ecosystems. Both non-target organisms showed different sensitivities to pollutants. The alga was more affected than the plant to each compound assayed, whether separately or mixed in EC50 proportion, and PFOA was more toxic to both bioindicators. An analysis of toxic chemical interactions covering the whole range of effect levels was conducted using the Combination Index method and indicated that synergism could be expected at low effect levels in higher plants, while for algae this type of interaction predominated at higher effect levels. Ecological risk assessment was performed by calculating the Hazard Quotient as the ratio between the measured environmental concentration and the predicted no-effect concentration, using our EC50 data derived from the mixture of pollutants. Acute hazard was found in the terrestrial compartment (soil or sediments). In the light of the data reported, we conclude that risk evaluation should include toxicological information on compound interactions that exert a toxic effect on non-target organisms.

Item Type: Article
Uncontrolled Keywords: Ibuprofen; Perfluorooctanoic acid; Pseudokirchneriella subcapitata; Risk assessment; Sorghum bicolor
Subjects: Q Science > QD Chemistry
Depositing User: José Ángel Gómez Martín
Date Deposited: 25 Oct 2013 08:53
Last Modified: 04 Mar 2014 09:04
URI: http://eprints.imdea-agua.org:13000/id/eprint/342

Actions (login required)

View Item View Item